CURRICULUM VITA: PILL-SOON SONG [September 23, 2003]
I.Name:PILL-SOON SONG
II.Position:Dow Chemical Professor (Emeritus), Department of Chemistry, Univ. of Nebraska-Lincoln, Lincoln, USA, and Director, Kumho Life & Environmental Science Laboratory, Gwangju, Korea
III.Education: B.S., Seoul National University, Suwon, Korea
M.S., Seoul National University, Seoul, Korea
Ph.D., University of California, Davis, California
Postdoctoral Fellow, Iowa State University, Ames, IA (with Professor David E. Metzler)
IV.Honors and Awards
 1975-1987Paul Whitfield Horn Professorship, Texas Tech University, Lubbock, TX
 1990-2002Dow Chemical Company Professorship, UNL
 1991Outstanding Research Award, American Society for Photobiology (based on work published through 1989/90).
 1996Outstanding Alumni Achievement Award, 90th Anniversary of the College of Agriculture and Life Sciences, Seoul National University, October, 1996
 1997Life Member (Elected), Korean Academy of Science and Technology Outstanding Research Achievement Medal, European Society for Photobiology, presented at the 1997 ESP Congress, Stresa, Italy, September, 1997.
 2000Lifetime Achievement Award, American Society for Photobiology/13th International Congress on Photobiology, San Francisco, July 1-6, 2000
 2000Outstanding Research and Creative Activity Award, State of Nebraska/University of Nebraska, Lincoln, March 29, 2000
 2000Ho-Am Prize in Science, The Ho-Am Foundation/Samsung Corporation, June 1, 2000
V.Professional Experience and Distinctions
 1996-2000President (elected), International Union of Photobiology
 1997-2001Member, NIH Biophysics & Biophysical Chemistry-A Study Section
 1997-presentDirector/Senior Executive Vice President, Kumho Life & Environmental Science Laboratory, Korea Kumho Petrochemical Co., Ltd
 2002-2005Board of Directors (elected), International Society for Plant Molecular Biology
 2004President, 14th International Union of Photobiology Congress on Photobiology, June 10-15, 2004, Jeju, Korea
 2002-2004President-Elect, Asia and Oceania Society for Photobiology
 2002-2004Chair, Gordon Research Conference on Sensory Photoreceptors and Signal Transduction, Ventura, CA, 2004
VI.Research Summary
  Studies of the molecular mechanisms of light signal transduction mediated by photobiological receptors (phytochrome and stentorin) through fluorescence, picosecond spectroscopy, anisotropy, circular dichroism, biochemical and site-specific mutagenesis. During the last ten years, research in my lab focused on the structure-function relationship of phytochromes and stentorian, resulting in the following findings:
 
(1)Chemical structures of ciliate phototaxis receptors stentorian and blepharismin were elucidated (1993 and 1997, respectively).
(2)The primary photoprocess of phytochrome proceeds in 25 picosends. (1989)
(3)The phytochrome phototransformation is accompanied by the amphiphilic alpha-helix formation in the N-terminal extreme of the photoactived form of phytochrome (Pfr); this conformation change is functionally important in plant cells in vivo (1987-1992).
(4)Phytochrome is posttranslationally modified (phosphorylated) in a phototransformation-dependent manner (1998-1999).
(5)The phytochrome-mediated light signaling in plants involves a small-mol-wt G-protein (1991, 2001).
(6)Nucleoside diphosphate kinase-2 (catalyzing the formation of GTP) found to interact with the photoactivated phytochrome (Pfr) as a positive upstream component of the phytochrome-mediated light signaling in Arabidopsis. The enzymatic activity is activated by the photoactivated Pfr-phytochrome (1999).
(7)Phytochrome-specific protein phosphatase (FYPP) found and its role in modulating the phytochrome-mediated flowering time elucidated (2002).
VII.Publications
 For the 1997-Present Period (University of Nebraska & Kumho Life and Environmental Science Laboratory)
 Original Articles
 
301.T.A. Wells, A. Losi, R. Dai, P. Scott, M. Anderson, J. Redepenning, S.-M. Park, J. Golbeck and P.-S. Song, Electron Transfer Quenching and Photoinduced EPR of Hypericin and the Ciliate Photoreceptor Stentorin, J. Phys. Chem., 101: 366-372 (1997).
302.E. Chen, V.N. Lapko, P.-S. Song and D.S. Kliger, Dynamics of the N-Terminus a-Helix Unfolding in the Photoreversion Reaction of Phytochrome A, Biochemistry, 36: 4903-4908 (1997).
303.P.-S. Song, M. H. Park and M. Furuya, Chromophore:Apoprotein Interactions in Phytochrome A, Plant Cell Environ., 20: 707-712 (1997).
304.G. Checcucci, R.S. Shoemaker, E. Bini, R. Cerny, N. Tao, J.-S. Hyon, D. Gioffre, F. Ghetti, F. Lenci and P.-S. Song, Chemical Structure of Blepharismin, the Photosensor Pigment for Blepharisma japonicum, J. Am. Chem. Soc., 119: 5762-5763,9588 (1997).
305.V. N. Lapko, X.-Y. Jiang, D.L. Smith, and P.-S. Song, Post-Translational Modification of Oat Phytochrome A: Phosphorylation of a Specific Serine in a Multiple Serine Cluster, Biochemistry, 36: 10595-10599 (1997).
306.S. H. Bhoo, T. Hirano, H.-Y. Jeong, J.-G. Lee, M. Furuya and P.-S. Song, Phytochrome Photochromism Probed by Site-Directed Mutations and Chromophore Esterification, J. Am. Chem. Soc., 119: 11717-11718 (1997).
307.H. Yi, P.-S. Song and G. Choi, Cloning and Characterization of Nucleoside Diphosphate Kinase 2 from Arabidopsis thaliana (Plant Gene Register 98-056). Plant Physiol. 116, 1604 (1998).
308.V.N. Lapko, X.-Y. Jiang, D.L. Smith and P.-S. Song, Surface Topography of Phytochrome A Deduced from Specific Chemical Modification with Iodoacetamide. Biochemistry, 36: 12526-12535 (1998).
309.N. Angelini, A. Quaranta, G. Checcucci, P.-S. Song and F. Lenci. Electron Transfer Fluorescence Quenching of Blepharisma japonicum Photoreceptor Pigments. Photochem. Photobiol.(Am. Soc. Photobiology), 68: 864-868 (1998).
310.V. N. Lapko, X.-Y. Jiang, D. L. Smith and P.-S. Song. Mass Spectrometric Characterization of Oat Phytochrome A: Isoforms and Posttranslational Modifications. Protein Science, 8: 1032-1044 (1999).
311.J.-S. Choi, Y.-H. Chung, C. Kim, M. Watanabe, P.-S. Song, L. Bogorad and Y.M. Park. Photomovement of the Gliding Cyanobacterium Synechocystis sp. PCC 6803. Photochem. Photobiol., 70: 95-102 (1999).
312.G. Choi, H. Yi, J. Lee, Y.-K. Kwon, M.S. Soh, B. Shin, Z. Luka, T.-R. Hahn and P.-S. Song. Phytochrome Signaling is Mediated Through Nucleotide Diphosphate Kinase 2. Nature, 401: 610-614 (1999).
313.P.-S. Song. Inter-Domain Signal Transmission within the Phytochromes. J. Biochem. Mol. Biol. 32: 215-225 (1999) (Invited Review)
314.C.-M. Park, J.-Y. Shim. S.-S. Yang, J.-G. Kang, J.-I. Kim, Z. Luka and P.-S. Song. Chromophore-Apoprotein Interactions in Synechocystis sp. PCC6803 Phytochrome Cph1. Biochemistry 39: 6349-6356 (2000).
315.C.-M. Park, J.-I. Kim, J.-H. Kang, S.-S. Yang, J.-G. Kang, J.-Y. Shim, Y.-H. Chung, Y.-M. Park and P.-S. Song. A Second Photochromic Bacteriophytochrome from Synechocystis sp. PCC6803: Spectral Analysis and Down-Regulation by Light. Biochemistry 39:10840-10847 (2000).
316.C.-M. Park, S.-H. Bhoo and P.-S. Song. Inter-Domain Crosstalk in the Phytochrome Molecules. In: Seminars in Cell and Developmental Biology, Edited by H. Smith, Academic Press. 11: 449-456 (2000).
317.M.-S. Soh, Y.-M. Kim, S,-J. Hahn and P.-S. Song. REP1, a bHLH Protein is Required for a Branch Pathway of Phytochrome A Signaling in Arabidopsis thaliana. Plant Cell, 12: 1-14 (2000).
318.P.-S. Song. Phototaxis. In: McGraw-Hill Yearbook in Science & Technology-2001, McGraw-Hill, New York, pp. 303-305 (2000).
319.Y.J. Im, C.-M. Park, J.-I. Kim, S.-S. Yang, J.-G. Kang, S.-H. Rho, J.I. Kim, W.K. Song, P.-S. Song and S.H. Eom. Crystallization and preliminary X-ray crystallographic studies of response regulator for cyanobacterial phytochrome, Rcp1. Acta Crystal. D:Biol. Crystal. 56:1446-1448 (2000).
320.P.-S. Song and C.-M. Park. A Molecular Model for Light Signal Perception and Interdomain Crosstalk in Phytochrome Photoreceptors. J. Photoscience, 7: 79-86 (2000) (Invited review).
321.Phun Bum Park and Pill-Soon Song. Subcellular Localization of GTP Binding Protein in Stentor coeruleus. J. Photosci. 7: 31-34 (2000).
 
Original Articles (2001-present)
 
322.C.-H. Bae, K. Tohyama, S.C. Lee, Y.P. Lim, H.I. Kim, P.-S. Song and H.Y. Lee. Efficient Plant Regeneration Using Mature Seed-Derived Callus in Zoysiagrass (Zoysia japonica Steud.). Kor. J. Plant Tissue Culture. 28: 61-67 (2001).
323.J.-G. Kang, J. Yun, D.-H. Kim, K.-S. Chung, S. Fujioka, J.-I. Kim, H.-W. Dae, S. Yoshida, S. Takatsuto, P.-S. Song and C.-M. Park. Light and Brassinosteroid Signals are Integrated via a Dark-Induced Small G Protein in Etiolated Seedling Growth. Cell , 105: 625-636 (2001).
324.B. Shin, G. Choi, H. Yi, Y. Yang, L. Cho, J. Kim, S. Lee, N.C. Paek, J.-H.Kim, P.-S. Song and G. Choi, AtMYB21, a Gene Encoding a Flower-specific Transcription Factor, is regulated by COP1. Plant J., 30: 23-32 (2002).
325.Y.-J. Im, S.-H. Rho, C.-M. Park, S.-S. Yang, J.-G. Kang, J.-Y. Lee, P.-S. Song and S. H. Eom. Crystal Strcuture of a Cyanobacterial Phytochrome Response Regulator. Protein Sci. 11: 614-624 (2002).
326.Y.-M. Kim, J.-Chang Woo, P.-S. Song and M.-S. Soh, HFR1, A Phytochrome-A Signalling Component, Acts in a Separate Pathway from HY5, downstream of COP1 in Arabidopsis thaliana. Plant J. 30: 711-719 (2002).
327.M.-S. Seo, C.-H. Bae, D.-O. Choi, S.-L. Rhim, S.-C. Seo, P.-S. Song and H.-Y. Lee. Investigation of Transformation Efficiency of Rice Using Agrobacterium tumefaciens and High Transformation of GPAT (Glycerol-3-phosphate acyltransferase) Gene Relative to Chilling Tolerance. Kor. J. Plant Biotech. 29: 85-92 (2002).
328.J.-I. Kim, G. V. Kozhukh and P.-S. Song. Phytochrome-mediated signal transduction pathways in plants. Biochem. Biophys. Res. Commun. 298: 457-463 (2002).
329.D.-H. Kim, J.-G. Kang, S.-S. Yang, K.-S. Chung, P.-S. Song and C.-M. Park. A Phytochrome-Associated Protein Phosphatase 2A Modulates Light Signals in Flowering Time Control in Arabidopsis. Plant Cell 14: 3043-3056 (2002)
330.K. Toyama, C.-H. Bae, T.-G. Kang, Y.-P. Lim, T. Adachi, K.-Z. Riu, P.-S. Song and H.Y. Lee. Production of Herbicide-Tolerant Zoysiagrass by Agrobacterium-Mediated Transformation. Mol. Cell. 16: 19-27 (2003)
331.C.-M. Park and P.-S. Song. Structure and Function of the Phytochromes: Light Regulation of Plant Growth and Development. J. Photosci. 10: 157-164.
332.J. Kim, H. Yi, G. Choi, B. Shin, P.-S. Song, and Giltsu Choi. Functional Characterization of PIF3 in Phytochrome-Mediated Light Signal Transduction. Plant Cell, in press (October, 2003).
333.G. Choi, J.-I. Kim, S.-W. Hong, B. Shin, G. Choi, H. Lee and P.-S. Song. The role of NDPK2, a Phytochrome Interacting Protein, in Cross-talk Between the Phytochrome-Mediated Light and Auxin Signalings in Arabidopsis. Submitted. (2003)
334.J.-I. Kim, Y. Shen, Y.-J. Han, D. Kirchenbauer, M.-S. Soh, F. Nagy, E. Schaefer and P.-S. Song. Phosphorylation of Phytochromes in the Plant Light Signaling. Plant Cell, submitted. (2002).