Publications
R. Shchepin, D. H. M. L. P. Navarathna, R. Dumitru, S. Lippold, K. W. Nickerson, and P. H. Dussault, Influence of heterocyclic farnesol analogs on quorum sensing and pathogenicity in Candida albicans. Bioorganic & Medicinal Chemistry, 2008, in press (doi:10.1016/j.bmc.2007.11.011, available online November 6, 2007).
P. H. Dussault and Chunping Xu, Fused Ring Oxetanes. Comprehensive Heterocylic Chemistry III, Elsevier, 2008, Chapter 2.06 (Chris Stevens, editor).
Guderian, David M.; Rasmussen, Heather E.; Wray, Curtis A.; Dussault, Patrick H.; Carr, Timothy P. Cholesterol-lowering properties of plant sterols esterified with beef tallow fatty acids in hamsters. Nutrition Research (New York, NY, United States) (2007), 27(5), 283-288.
Rasmussen, Heather E.; Guderian, David M., Jr.; Wray, Curtis A.; Dussault, Patrick H.; Schlegel, Vicki L.; Carr, Timothy P. Reduction in cholesterol absorption is enhanced by stearate-enriched plant sterol esters in hamsters. Journal of Nutrition (2006), 136(11), 2722-2727.
Schwartz, Chris; Raible, Joseph; Mott, Kyle; Dussault, Patrick H. 'Reductive ozonolysis' via a new fragmentation of carbonyl oxides. Tetrahedron (2006), 62(46), 10747-10752.
Schwartz, Chris; Raible, Joseph; Mott, Kyle; Dussault, Patrick H.. Fragmentation of Carbonyl Oxides by N-Oxides: An Improved Approach to Alkene Ozonolysis.Department of Chemistry, University of Nebraska Lincoln, Lincoln, NE, USA. Organic Letters (2006), 8(15), 3199-3201.
A Dai, Peng; Trullinger, Tony K.; Liu, Xuejun; Dussault, Patrick H. Asymmetric Synthesis of 1,2-Dioxolane-3-acetic Acids: Synthesis and Configurational Assignment of Plakinic Acid. Journal of Organic Chemistry (2006), 71(6), 2283-2292.
Zaleta-Rivera, Kathia; Xu, Chunping; Yu, Fengan; Butchko, Robert A. E.; Proctor, Robert H.; Hidalgo-Lara, Maria E.; Raza, Ashraf; Dussault, Patrick H.; Du, Liangcheng. A Bidomain Nonribosomal Peptide Synthetase Encoded by FUM14 Catalyzes the Formation of Tricarballylic Esters in the Biosynthesis of Fumonisins. Biochemistry (2006), 45(8), 2561-2569.
Schwartz, Chris; Dussault, Patrick H. In situ reductive ozonolysis of olefins: Capture and decomposition of carbonyl oxides by N-oxides. Abstracts of Papers, 232nd ACS National Meeting, San Francisco, CA, United States, Sept. 10-14, 2006, ORGN-486.
Xu, Chunping; Raible, Joseph M.; Dussault, Patrick H. Total Synthesis of Peroxyacarnoates A and D: Metal-Mediated Couplings as a Convergent Approach to Polyunsaturated Peroxides. Organic Letters (2005), 7(12), 2509-2511.
R. Shchepin, P. H. Dussault, K. W. Nickerson, R. Dumitru, A. Atkin, Exploring the mechanism of quorum-sensing in Candida albicans with synthetic farnesol analogs. Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005, MEDI-388.
R. Shchepin, R. Dumitru, K. W. Nickerson, M. Lund, P. H. Dussault. Biologically active fluorescent farnesol analogs. Chemistry & Biology 2005, 12, 639-641. New Approaches to Cyclic Peroxides P. Dussault, Abstracts, 40th Midwest Regional Meeting of the American Chemical Society, Joplin, MO, United States, October 26-29, 2005, LIN05-079.
P. Dussault, C. Xu. Studies Toward the Asymmetric Synthesis of Peroxyplakoric Acids. Abstracts, 40th Midwest Regional Meeting of the American Chemical Society, Joplin, MO, United States, October 26-29, 2005, LIN05-163.
P. Dussault, C. Xu, J. M. Raible. Studies toward the asymmetric synthesis of peroxyacarnoic acids. Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005, ORGN-582.
P. Dai, P. H. Dussault. Intramolecular opening of oxetanes: A stereospecific route to cyclic peroxides. Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005, ORGN-514.
Shchepin, Roman; Dumitru, Raluca; Nickerson, Kenneth W.; Lund, Miranda; Dussault, Patrick H. Biologically active fluorescent farnesol analogs. Chemistry & Biology (2005), 12(6), 639-641.
Ahmed, Aqeel; Dussault, Patrick H. Stereoselective allylation of chiral monoperoxyacetals. Tetrahedron (2005), 61(19), 4657-4670.
Dai, Peng; Dussault, Patrick H. Intramolecular Reactions of Hydroperoxides and Oxetanes: Stereoselective Synthesis of 1,2-Dioxolanes and 1,2-Dioxanes. Organic Letters (2005), 7(20), 4333-4335.
K. Zaleta-Rivera, R. S. Bojja, H. Yi, C. Xu, P. H. Dussault, L. Du. FUM13 and FUM14, Two Genes Involving in the Biosynthesis of Mycotoxin Fumonisins in Fusarium verticillioides. Abstracts, 39th Midwest Regional Meeting of the American Chemical Society, Manhattan, KS, United States, October 20-22 2004, MID04-236.
P. H. Dussault, P. Dai, X. Liu. The bioactive peroxide plakinic acid A: Structural determination via asymmetric synthesis. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, United States, August 22-26, 2004, ORGN-354.
A. Ahmed, P. H. Dussault. 1,2,4-Trioxepanes as redox sensitive protecting groups for carbonyls. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, United States, August 22-26, 2004, ORGN-603.
Dai, Peng; Dussault, Patrick H.; Trullinger, Tony K. Magnesium/Methanol: An Effective Reducing Agent for Peroxides. Journal of Organic Chemistry (2004), 69(8), 2851-2852.
Ahmed, Aqeel; Dussault, Patrick H. 1,2,4-Trioxepanes: Redox-cleavable protection for carbonyl groups. Organic Letters (2004), 6(20), 3609-3611.
Dussault, Patrick H.; Xu, Chunping. Curtius rearrangement and Wolff homologation of functionalized peroxides. Tetrahedron Letters (2004), 45(40), 7455-7457.
Ahmed, Aqeel; Crawford, Terry; Gould, Stephanie; Ha, Y. S.; Hollrah, Monica; Noor-E-Ain, Farhana; Dickman, Martin B.; Dussault, Patrick H. Synthesis of (R)- and (S)-10,16-dihydroxyhexadecanoic acid: cutin stereochemistry and fungal activation. Phytochemistry (Elsevier) (2003), 63(1), 47-52.
Shchepin, Roman; Hornby, Jacob M.; Burger, Erin; Niessen, Timothy; Dussault, Patrick; Nickerson, Kenneth W. Quorum Sensing in Candida albicans Probing Farnesol's Mode of Action with 40 Natural and Synthetic Farnesol Analogs. Chemistry & Biology (2003), 10(8), 743-750.
J. J. Stezowski, P. H. Dussault. Nearly a decade of experience with NSF-REU programs in chemistry at the University of Nebraska-Lincoln. Abstracts of Papers, 223rd ACS National Meeting, Orlando, FL, United States, April 7-11, 2002, CHED-146.
Chiral Intermediates. Edited by Cynthia A. Challener. Ashgate Publishing, Burlington, VT. 2001. xxiii + 804 pp. 18 * 25 cm. ISBN 0-5660-8412-0. $295.00 P. Dussault, Journal of Medicinal Chemistry 2002, 45, 1392.
E. C. Burger, R. Shchepin, P. Dussault, J. Hornby, K. W. Nickerson. Synthetic analogs of a fungal Quorum-Sensing Molecule. Abstracts of Papers, 223rd ACS National Meeting, Orlando, FL, United States, April 7-11, 2002, CHED-843.
Dussault, Patrick H.; Trullinger, Tony K.; Noor-e-Ain, Farhana. Opening of Substituted Oxetanes with H2O2 and Alkyl Hydroperoxides: Stereoselective Approach to 3-Peroxyalcohols and 1,2,4-Trioxepanes. Organic Letters (2002), 4(26), 4591-4593.
P. H. Dussault, J. M. Raible, E. C. Burger, P. M. Unverzagt. Directed nucleophilic addition to carbonyl oxides: Aprotic, reductive, and asymmetric methods. Abstracts of Papers, 222nd ACS National Meeting, Chicago, IL, United States, August 26-30, 2001, ORGN-321.
Hornby, Jacob M.; Jensen, Ellen C.; Lisec, Amber D.; Tasto, Joseph J.; Jahnke, Brandon; Shoemaker, Richard; Dussault, Patrick; Nickerson, Kenneth W. Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol. Applied and Environmental Microbiology (2001), 67(7), 2982-2992.
P. H. Dussault, T. K. Trullinger, S. Cho-Schultz. Chiral O- and S-silyl ketene acetals: Lewis acid-mediated reaction with peroxyacetals and acetals. Abstracts of Papers, 220th ACS National Meeting, Washington, DC, United States, August 20-24, 2000, ORGN-083.
"Chiral silyl ketene acetals from thioesters: Reaction with acetals and peroxyacetals to form 3-alkoxy- and 3-peroxyalkanoates" P. H. Dussault, Tony K. Trullinger and Sujin Cho-Shultz Tetrahedron 2000, 9213-9220.
"Synthesis of Peroxides through Peroxycarbenium-Mediated C-C Bond Formation: Scope and Limitations" P. H. Dussault, R. Lee, H. J. Lee, I. Q. Lee, Q. J. Niu, J. A Schultz and U. R. Zope J. Org. Chem. 2000, 65, 8407.
"Ozonolysis in the Presence of Lewis Acids: Directed Addition to Carbonyl Oxides" Dussault, P. H.; Raible, J. M. Org. Lett, 2000, 2, 3377-3379.
"Selectivity in Lewis acid-mediated fragmentations of peroxides and ozonides: application to the synthesis of alkenes, homoallyl ethers, and 1,2-dioxolanes", Dussault, P. H.; Lee, H.-J.; Liu, X., Perkin 1 2000, 3006-3013.
"Reaction of peroxyacetals with silyl ketene acetals: synthesis of 3-peroxyalkanoates and 3-peroxyalkanals", Dussault, P. H.; Lee, R. J.; Schultz, J. A.; Suh, Y. S., Tetrahedron Lett. 2000, 41, 5457-5460.
"Peroxides as oxidative enzyme inhibitors: Mechanism-based inhibition of a cysteine protease by an amino acid ozonide" Patrick H. Dussault*, A. Denise George and Tony K. Trullinger, Bioorg. Med. Chem. Lett.1999, 9, 3255-3258
"Diastereoselective Addition of Singlet Oxygen to Z-Allylic Alcohols: Effect of Neighboring Functional Groups" Patrick H. Dussault*, and Jeffrey A. Schultz J. Org. Chem., 1999, 64, 8419-8422.
"Lewis Acid-Mediated Displacments of Alkoxydioxolanes: Synthesis of a 1,2-Dioxolanes Natural Product" Patrick H. Dussault and Xuejun Liu, Organic Lett., 1999, 1391-3.
"SnCl4-mediated reaction of ozonides with allyltrimethylsilane: formation of 1,2-dioxolanes" Patrick H. Dussault and Xuejun Liu, Tetrahedron Lett 1999, 40, 6553-6.
"Photooxygenation of chiral dienol ethers: asymmetric synthesis of alkoxydioxines" P. H. Dussault, Q. Han, D. Sloss and David Symonsbergen Tetrahedron, 1999, 55, 11437-54
"Allylmetal-directed addition of 1O2: Scope, mechanism, and synthetic utility" P. H. Dussault, C. T. Eary, R. J. Lee and U. R. Zope, J. Chem. Soc., Perkins 1, 1999, 2189-2204.
"Total Synthesis of the Alkoxydioxines (+) and (-) Chondrillin and (+) and (-) Plakorin through Singlet Oxygenation/Radical Rearrangement" Patrick H. Dussault, Charles T. Eary, Kevin R. Woller. J. Org. Chem.1999, 64, 1789-97.
"Metathesis-based Synthesis of Jasmonate and Homojasmonate Lactones, Candidates for Extracellular Quorum Sensing Molecules in Candida albicans". Su C. Cho, Patrick H. Dussault*, Amber D. Lisec, Ellen C. Jensen and Kenneth W. Nickerson*, J. Chem. Soc., Perkins Trans 1. 1999, 193.
"Application of the Sonogashira Coupling Reaction Towards the Stereoselective Synthesis of Chiral 1,3-Dienol Ethers", Patrick H. Dussault*, Darby G. Sloss, and David J. Symonsbergen Synlett 1999 1387.
"Hydrogen-Donating Mechamism of Rosmariquinone, an Antioxidant Found in Rosemary" C. A. Hall III, S. L. Cuppett*, and P. Dussault J. Am. Oil. Chem. Soc. 1998, 75, 1147.
"Palladium Mediated Carbon-Carbon Bond Forming Reactions as a New Method for the Synthesis of Peroxides and Hydroperoxides" Patrick H. Dussault and C. Todd Eary, J. Am. Chem. Soc. 1998, 120, 7133.
"Synthesis and Antioxidant Activity of Rosmariquinone and Several Analogues" Clifford A. Hall III, Susan L. Cuppett*, and Pat Dusssault, J. Agr. Food. Chem. 1998, 46, 1303-1310.
"Singlet Oxygenation/Radical Rearrangement as an Approach to 1,4-Dioxygenated Peroxides: Asymmetric Total Synthesis of Plakorin and a Revision in the Stereochemical Assignment of Chondrillin" Patrick Dussault and Kevin Woller J. Am. Chem. Soc.1997, 119, 3824-3825.
"Approaches to the Stereoselective Dioxygenation of Alkenes: Chiral Phosphite Ozonides" Patrick H. Dussault and Kevin R. Woller, J. Org. Chem. 1997, 52, 1556-1559.
"Auxiliary-Directed Peroxidation of 1,4-Dienes" P. H. Dussault*, T. Anderson, M. R. Hayden, K. Koeller and Q. J. Niu, Tetrahedron 1996, 52, 12381-12398.
"Biphasic Singlet Oxygenation with a Perfluoroalkylated Photosensitizer" Steven DiMagno*, Patrick Dussault*, and Jeff A. Schultz, J. Am. Chem. Soc. 1996, 118, 5312.
"Simple Procedures For Quantification And Reuse Of Common Organic Solvent Mixtures" Patrick Dussault* and Kevin Woller, The Chemical Educator, 1996, 1, 1-6.
"Synthesis of 1,2-Dioxanes, 1,2,4-Trioxanes, and 1,2,4-Trioxepanes via Cyclizations of Unsaturated Hydroperoxyacetals" Patrick H. Dussault and Donald R. Davies Tetrahedron Lett. 1996, 37, 463-466.
"Stereoselectivity of Addition to Chiral Carbonyl Oxides" P. H. Dussault and U. R. Zope, J. Org. Chem. 1995, 60, 8218-8222.
"The Peroxide Changes Everything" P. H. Dussault Synlett, 1995, 997-1003
"Synthesis of E,E-Diene Hydroperoxides via Photoisomerization of Protected Hydroperoxides" Patrick Dussault* , In Quen Lee, and Todd Eary,Lipids, 1995, 30, 591-594
" Reactions of Hydroperoxides and Peroxides" P. H. Dussault, in Active Oxygen in Chemistry, C. S. Foote, J. S. Valentine, A. Greenberg, J. F. Liebman, eds. Blackie Academic and Professional, London, 1995, 141-203.
"Chemoselective Hydrogenation of Unsaturated Peroxides" P. H. Dussault*, S. E. Kreifels, and I. Q. Lee, Syn. Comm., 1995, 25, 2613-2621.
"Hydroperoxide-Mediated C-C Bond Formation: Synthesis of 1,2-Dioxolanes from Alkoxyhydroperoxides in the Presence of Lewis Acids P. H. Dussault* and U. R. Zope, Tetrahedron Lett. 1995, 36, 3655-3658.
"Reaction of 1O2 with Alkoxyallylstannanes: Synthesis of 1,2-Dioxolanes and Allyl Hydroperoxides" P.H. Dussault and U. R. Zope, Tetrahedron Lett., 1995, 36, 2187-2190.
"Peroxycarbenium-Mediated C-C Bond Formation: Synthesis of Cyclic Peroxides from Monoperoxyketals" P. H. Dussault*, H-J. Lee, and Q. J. Niu J. Org. Chem. 1995, 60, 784-785.
"A Chemoenzymatic Approach to Hydroperoxyeicosatetraenoic Acids (HPETEs): Total Synthesis of 5(S)-HPETE"-P. H. Dussault* and I. Q. Lee, J. Org. Chem. 1995, 60, 218-226.
"2-(2-methoxyethoxy)-prop-2-yl Hydroperoxide: A More Easily Handled Reagent for the Synthesis of Hydroperoxides" P. H. Dussault*, U. R. Zope, and T. A. Westermeyer, J. Org. Chem. 1994, 59, 8267-8268.
"Stereoselective Dioxygenation of Enoates" P. H. Dussault*, K. Woller, M. C. Hillier, Tetrahedron, 1994, 50, 8929-8940.
"Stereospecific Dioxygenation of Allylstannanes: Synthesis of Enantiomerically Enriched Allyl Hydroperoxides" P.H. Dussault* and R. Lee J. Am. Chem. Soc. 1994, 116, 4485-4486.
"An Organometallic Approach to Peroxyketals" P. H. Dussault*, A. Sahli, T. Westermeyer, J. Org. Chem. 1993, 58, 5469-5474.
"Peroxycarbenium Mediated Carbon-Carbon Bond Formation: Synthesis of Peroxides from Monoperoxyketals" P.H. Dussault* and I. Q. Lee, J. Am.. Chem. Soc. 1993, 115, 6458-59.
"Total Synthesis of 15-HPETE" P.H. Dussault* and In Quen Lee, J. Org. Chem. 1992, 57, 1952-1953.
"Auxiliary-Directed Dioxygenation: Stereoselective Synthesis of a Diene Hydroperoxide" P.H. Dussault* and M.R. Hayden, Tetrahedron Letters, 1992, 33, 443-446.
"2-Methoxyprop-2-yl Hydroperoxide: A Convenient Reagent for the Synthesis of Hydroperoxides and Peracids." P.H. Dussault* and A. Sahli, J. Org. Chem. 1992, 57, 1009.
"A New Synthon for Optically Active Diene Hydroperoxides" P.H. Dussault*, I.Q. Lee, and S. Kreifels, J. Org. Chem. 1991, 56, 4087-9.
"An Olefination-Based Route to Unsaturated Hydroperoxides" P.H. Dussault* and A. Sahli, Tetrahedron Lett. 1990, 31, 5117-5120.
